Sandrine Duverne


Center for the Neurobiology of Learning and Memory
Bonney Research Laboratory
University of California, Irvine
Irvine, CA 92697-3800

Phone: 949-824-8861
Fax: 949-824-4807
Email: sduverne@uci.edu

Please see my CV or contact me for more details.

Research Interests
 

Healthy cognitive aging is characterized by a decline in cognitive performance. This decline is, however, not uniform across and within cognitive domains.

For example, episodic memory shows a marked decline with increasing age compared to other types of memory like semantic or implicit memory. Neuroimaging studies have suggested that the decline of performance in episodic memory could be accounted for by age-related changes in neural activity at the time of both encoding and retrieval. Further, multiple patterns of age-related changes in neural activity have been observed for both encoding and retrieval memory processes, such as decreased, maintained, or increased activity compared to younger adults. 

 My research projects aim at identifying the combination of mechanisms that accounts for age-related changes in the neural activity associated with episodic memory and, ultimately, for age-related changes in memory performance. In this perspective, my work consists in specifying the effects of age on the neural correlates of distinct memory processes and in exploring the impact of individual variables that co-vary with memory performance.

Techniques:

 - Functional magnetic resonance imaging (fMRI)

 - Event-related potentials (ERPs)

 - Neuropsychological assessments

Selected Publications

 Duverne, S., Habibi, A., & Rugg, M.D. (submitted). Regional specificity of age effects on the neural correlates of episodic retrieval.

 Duverne, S., Motamedinia, S., & Rugg, M.D. (in preparation). Effects of age on retrieval cue processing revealed by ERPs in recognition and source memory tasks.

 Duverne, S., Gazzaley, A., & D’Esposito, M. (in preparation). Distinct top-down control networks associated with the modulation of activity in visual association cortex: the impact of encoding strategies in a working memory task.

 Duverne, S., & Lemaire, P. (2004). Adult age-related changes in arithmetic problem verification strategies. Journal of Gerontology : Psychological Sciences, 59B, 135-142.

 Duverne, S., Lemaire, P., & Michel, B.F. (2003). Alzheimer’s disease disrupts arithmetic facts retrieval processes but not arithmetic strategy selection. Brain and Cognition, 52, 302-318.

Recent Presentations

Duverne, S., Habibi, A., & Rugg, M.D. (2006). Age-related differences in neural correlates of retrieval of visual episodic information. Society For Neuroscience, Atlanta, GA, USA. Poster.

Duverne, S., Gazzaley, A., & D’Esposito, M. (2006). The effects of working-memory encoding strategies on modulation of visual association cortex. Cognitive Neuroscience Society, San Francisco, CA, USA. Poster.

 Duverne, S., Rissman, J., & D’Esposito, M. (2005). Prefrontal and parietal network mediating strategy use in arithmetic problem solving. Cognitive Neuroscience Society, New York, NY, USA. Poster.

Duverne, S. & D’Esposito, M. (2004). Prefrontal contributions to strategy selection: choice, execution, switching, and incongruity in an arithmetic task. Society For Neuroscience, San Diego, CA, USA. Oral communication.

 

Please see my CV for a complete list of my publications and presentations.